Mycobacterium tuberculosis-Specific Antigen Rv3619c Effectively Alleviates Allergic Asthma in Mice

• Autori principali: Hussain A. Safar (Autore), Ahmed Z. El-Hashim (Autore), Hanady Amoudy (Autore), Abu Salim Mustafa (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Despite significant advances, asthma remains a cause of premature death, and current treatments are suboptimal. Antigen-specific Th2 cells and their cytokines are primary mediators of the pathophysiological changes seen in asthma. Studies in animal models have shown that mycobacteria can suppress th...