Decreased Lung Tumor Development in SwAPP Mice through the Downregulation of CHI3L1 and STAT 3 Activity via the Upregulation of miRNA342-3p

• Main Authors: Dong Hun Lee (Author), Ki Cheon Kim (Author), Chul Ju Hwang (Author), Kyung Ran Park (Author), Young Suk Jung (Author), Sun Young Kim (Author), Ji Young Kim (Author), Ju Kyung Song (Author), Min Ji Song (Author), Min Ki Choi (Author), Dae Youn Hwang (Author), Sang-Bae Han (Author), Jin Tae Hong (Author)
• Format: Book
• Published: Elsevier, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously found that lung tumor development was reduced in a presenilin (PS) Alzheimer's disease (AD) mouse model. Here, we investigated whether this reducing effect could occur in a different AD mouse model. We investigated urethane-induced (1 mg/g) lung tumor development and melanoma grow...