Efficacy of a Combined Antiplatelet Therapy Is Not Affected by a Simultaneous Binding of Cangrelor and PSB 0777 to Albumin

• Glavni autori: Joanna Wzorek (Autor), Radosław Bednarek (Autor), Cezary Watala (Autor), Magdalena Boncler (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Concurrent administration of two drugs may complicate the management of acute coronary syndromes: competitive drug displacement diminishes drug binding and alters drug pharmacodynamics. We investigated the interaction of two antiplatelet compounds (PSB 0777 and cangrelor) with human serum albumin (H...