In silico Identification and Mechanism Exploration of Hepatotoxic Ingredients in Traditional Chinese Medicine

• Main Authors: Qihui Wu (Author), Chuipu Cai (Author), Pengfei Guo (Author), Meiling Chen (Author), Xiaoqin Wu (Author), Jingwei Zhou (Author), Yunxia Luo (Author), Yidan Zou (Author), Ai-lin Liu (Author), Qi Wang (Author), Zaoyuan Kuang (Author), Jiansong Fang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Backgrounds and AimsRecently, a growing number of hepatotoxicity cases aroused by Traditional Chinese Medicine (TCM) have been reported, causing increasing concern. To date, the reported predictive models for drug induced liver injury show low prediction accuracy and there are still no related repor...