Enhancing the Antipsychotic Effect of Risperidone by Increasing Its Binding Affinity to Serotonin Receptor via Picric Acid: A Molecular Dynamics Simulation

• Үндсэн зохиолчид: Majid Alhomrani (Зохиогч), Walaa F. Alsanie (Зохиогч), Abdulhakeem S. Alamri (Зохиогч), Hussain Alyami (Зохиогч), Hamza Habeeballah (Зохиогч), Heba A. Alkhatabi (Зохиогч), Raed I. Felimban (Зохиогч), John M. Haynes (Зохиогч), Sonam Shakya (Зохиогч), Bassem M. Raafat (Зохиогч), Moamen S. Refat (Зохиогч), Ahmed Gaber (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2022-02-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The aim of this study was to assess the utility of inexpensive techniques in evaluating the interactions of risperidone (Ris) with different traditional π-acceptors, with subsequent application of the findings into a Ris pharmaceutical formulation with improved therapeutic properties. Molecular dock...