Aberrant SOX10 and RET expressions in patients with Hirschsprung disease

• Main Authors: Gunadi (Author), Verrell Christopher Amadeus (Author), Fadila Dyah Trie Utami (Author), Fiqih Vidiantoro Halim (Author), Nabilah Anisa Novebri (Author), Rahaditya Alrasyidi Hanggoro (Author), Avinindita Nura Lestari (Author), Kristy Iskandar (Author), Andi Dwihantoro (Author), Eko Purnomo (Author)
• Format: Book
• Published: BMC, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background HSCR is a complex genetic disorder characterized by the absence of ganglion cells in the intestine, leading to a functional obstruction. It is due to a disruption of complex signaling pathways within the gene regulatory network (GRN) during the development of the enteric nervous...