UGT2B7 gene polymorphism and linkage disequilibrium in pediatric epileptic patients and their influence on sodium valproate monotherapy: A cohort study

• Main Authors: Sachidananda Adiga (Author), Nandit PB (Author), Usha Adiga (Author), Vijaya Shenoy (Author)
• 格式: 图书
• 出版: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Background: Uridine 5'-diphospho glucuronosyl transferase (UGT) is the main enzyme responsible for the glucuronide conjugation, the principal metabolic pathway of sodium valproate. The objective of the study was to explore if there was an association between the UGT2B7 genetic polymorphism and...