Normalization of B Cell Subsets but Not T Follicular Helper Phenotypes in Infants With Very Early Antiretroviral Treatment

• Main Authors: Sharon Shalekoff (Author), Shayne Loubser (Author), Bianca Da Costa Dias (Author), Renate Strehlau (Author), Stephanie Shiau (Author), Shuang Wang (Author), Yun He (Author), Elaine J. Abrams (Author), Louise Kuhn (Author), Caroline T. Tiemessen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Infant HIV-1-infection is associated with high morbidity and mortality if antiretroviral treatment (ART) is not initiated promptly. We characterized development of circulating T follicular helper cells (cTfh) and their relationship to naïve/memory B cell subsets in a cohort of neonate...