RNA-Guided CRISPR-Cas9 System-Mediated Engineering of Acute Myeloid Leukemia Mutations

RNA-Guided CRISPR-Cas9 System-Mediated Engineering of Acute Myeloid Leukemia Mutations

Current acute myeloid leukemia (AML) disease models face severe limitations because most of them induce un-physiological gene expressions that do not represent conditions in AML patients and/or depend on external promoters for regulation of gene expression/repression. Furthermore, many AML models ar...

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Main Authors: Oliver Brabetz (Author), Vijay Alla (Author), Linus Angenendt (Author), Christoph Schliemann (Author), Wolfgang E. Berdel (Author), Maria-Francisca Arteaga (Author), Jan-Henrik Mikesch (Author)
Format: Book
Published: Elsevier, 2017-03-01T00:00:00Z.
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