7-Hydroxycoumarin Attenuates Colistin-Induced Kidney Injury in Mice Through the Decreased Level of Histone Deacetylase 1 and the Activation of Nrf2 Signaling Pathway

Colistin has been considered as the last line of defense against Gram-negative bacterial infections, however, the potential nephrotoxicity limited its clinical use. 7-Hydroxycoumarin (7-HC) possesses many beneficial pharmacological activities. This study aimed to investigate the nephroprotective effe...

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Main Authors: Jian Wang (Author), Muhammad Ishfaq (Author), Qianqian Fan (Author), Chunli Chen (Author), Jichang Li (Author)
Format: Book
Published: Frontiers Media S.A., 2020-07-01T00:00:00Z.
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