Hyperuricemia causes kidney damage by promoting autophagy and NLRP3-mediated inflammation in rats with urate oxidase deficiency

Epidemiological research has shown that elevated serum urate concentration is a risk factor for the development of kidney disease; however, the mechanisms underlying this process have not yet been elucidated. To examine the role of urate in the kidney, we used Wistar rats to functionally disrupt exp...

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Main Authors: Mian Wu (Author), Yiwen Ma (Author), Xiaoting Chen (Author), Nan Liang (Author), Shen Qu (Author), Haibing Chen (Author)
Format: Book
Published: The Company of Biologists, 2021-03-01T00:00:00Z.
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3rd Floor Main Library

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