Palindromic carbazole derivatives: unveiling their antiproliferative effect via topoisomerase II catalytic inhibition and apoptosis induction

• Autori principali: Mateusz Olszewski (Autore), Natalia Maciejewska (Autore), Anoop Kallingal (Autore), Agnieszka Chylewska (Autore), Aleksandra M. Dąbrowska (Autore), Małgorzata Biedulska (Autore), Mariusz Makowski (Autore), José M. Padrón (Autore), Maciej Baginski (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

AbstractHuman DNA topoisomerases are essential for crucial cellular processes, including DNA replication, transcription, chromatin condensation, and maintenance of its structure. One of the significant strategies employed in cancer treatment involves the inhibition of a specific type of topoisomeras...