Novel in vitro pharmacodynamic model simulating ofloxacin pharmacokinetics in the treatment of Pseudomonas aeruginosa biofilm-associated infections

• Main Authors: Ayman M. Noreddin (Author), Walid F. Elkhatib (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2009-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Summary: Objectives: The conventional in vitro models simulate pharmacodynamics of antibiotics in the treatment of planktonic Pseudomonas aeruginosa. In this study, we propose a novel pharmacodynamic model of ofloxacin activity in the treatment of P. aeruginosa biofilm. Methods: P. aeruginosa biofil...