Functional requirement of alternative splicing in epithelial-mesenchymal transition of pancreatic circulating tumor

• Main Authors: Lixing Xiao (Author), Haoxiu Sun (Author), Rui Cheng (Author), Rongrong Yang (Author), Xiyun Jin (Author), Zhaochun Xu (Author), Yideng Cai (Author), Yuexin Yang (Author), Fenglan Pang (Author), Guangfu Xue (Author), Pingping Wang (Author), Qinghua Jiang (Author), Huan Nie (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Circulating tumor cells (CTCs) that undergo epithelial-to-mesenchymal transition (EMT) can provide valuable information regarding metastasis and potential therapies. However, current studies on the EMT overlook alternative splicing. Here, we used single-cell full-length transcriptome data and mRNA s...