Endothelin potentiates TRPV1 via ET_Areceptor-mediated activation of protein kinase C

• Main Authors: Furkert Jens (Author), Schaefer Michael (Author), Eichhorst Jenny (Author), Mousa Shaaban S (Author), Kepura Frauke (Author), Zöllner Christian (Author), Plant Tim D (Author), Stein Christoph (Author), Oksche Alexander (Author)
• Format: Book
• Published: SAGE Publishing, 2007-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Endothelin-1 (ET-1) both stimulates nociceptors and sensitizes them to noxious stimuli, an effect probably mediated by the ET_Areceptor (ET_AR) expressed in sensory neurons. The cellular m...