Current automated 3D cell detection methods are not a suitable replacement for manual stereologic cell counting

• Main Authors: Christoph eSchmitz (Author), Brian S Eastwood (Author), Susan J Tappan (Author), Jack R Glaser (Author), Daniel A Peterson (Author), Patrick R Hof (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stereologic cell counting has had a major impact on the field of neuroscience. A major bottleneck in stereologic cell counting is that the user must manually decide whether or not each cell is counted according to three-dimensional (3D) stereologic counting rules by visual inspection within hundreds...