Fluoroenesulphonamides: N-sulphonylurea isosteres showing nanomolar selective cancer-related transmembrane human carbonic anhydrase inhibition
After hydrofluorination of ynesulphonamides in superacid or in the presence of hydrofluoric acid/base reagents, a series of α-fluoroenamides has been synthesised and tested for the inhibition of carbonic anhydrase (CA, EC 4.2.1.1) isoforms. This study reveals a new, highly selective family of cancer...
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Main Authors: | , , , , , , |
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Format: | Book |
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Taylor & Francis Group,
2018-01-01T00:00:00Z.
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Connect to this object online.3rd Floor Main Library
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A1234.567 |
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Copy 1 | Available |