An insight into tumoral hypoxia: the radiomarkers and clinical applications

• Prif Awduron: Ana Margarida Abrantes (Awdur), Maria Elisa Serra (Awdur), Dina Murtinho (Awdur), Antonio Rocha Gonsalves (Awdur), Maria Filomena Botelho (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2011-12-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Tumoral hypoxia is related to severe structural abnormalities of tumor microvessels, leading to deteriorated O2 diffusion. This decreased O2 concentration in cancer cells compromises cellular functions, besides being responsible for resistance to radiation therapy. Consequently, it is very important...