AKT Inhibitors: New Weapons in the Fight Against Breast Cancer?

• मुख्य लेखकों: Federica Martorana (लेखक), Gianmarco Motta (लेखक), Giuliana Pavone (लेखक), Lucia Motta (लेखक), Stefania Stella (लेखक), Silvia Rita Vitale (लेखक), Livia Manzella (लेखक), Paolo Vigneri (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The serine/threonine kinase AKT is a key component of the PI3K/AKT/mTOR signaling pathway as it exerts a pivotal role in cell growth, proliferation, survival, and metabolism. Deregulation of this pathway is a common event in breast cancer including hormone receptor-positive (HR+) disease, HER2-ampli...