AKT Inhibitors: New Weapons in the Fight Against Breast Cancer?

• প্রধান লেখক: Federica Martorana (লেখক), Gianmarco Motta (লেখক), Giuliana Pavone (লেখক), Lucia Motta (লেখক), Stefania Stella (লেখক), Silvia Rita Vitale (লেখক), Livia Manzella (লেখক), Paolo Vigneri (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The serine/threonine kinase AKT is a key component of the PI3K/AKT/mTOR signaling pathway as it exerts a pivotal role in cell growth, proliferation, survival, and metabolism. Deregulation of this pathway is a common event in breast cancer including hormone receptor-positive (HR+) disease, HER2-ampli...