Synthesis and Biological Evaluation of Structurally Varied 5'-/6'-Isonucleosides and Theobromine-Containing <i>N</i>-Isonucleosidyl Derivatives

Isonucleosides are rather stable regioisomeric analogs of nucleosides with broad therapeutic potential. We have previously demonstrated the ability of 5′ and 6′-isonucleosides to inhibit the activity of acetylcholinesterase, a major target for Alzheimer’s disease therapy. Continuing with our researc...

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Main Authors: Nuno M. Xavier (Author), Eduardo C. de Sousa (Author), Margarida P. Pereira (Author), Anne Loesche (Author), Immo Serbian (Author), René Csuk (Author), M. Conceição Oliveira (Author)
Format: Book
Published: MDPI AG, 2019-07-01T00:00:00Z.
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3rd Floor Main Library

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