Atorvastatin population pharmacokinetics in a real‐life setting: Influence of genetic polymorphisms and association with clinical response

• Main Authors: Gabriel Stillemans (Author), Adrien Paquot (Author), Giulio G. Muccioli (Author), Emilia Hoste (Author), Nadtha Panin (Author), Anders Åsberg (Author), Jean‐Luc Balligand (Author), Vincent Haufroid (Author), Laure Elens (Author)
• Format: Book
• Published: Wiley, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The purpose of this study was to investigate the potential clinical relevance of estimating the apparent clearance (CL/F) of atorvastatin through population pharmacokinetic (PopPK) modeling with samples collected in a real‐life setting in a cohort of ambulatory patients at risk of cardiovas...