Hepcidin gene polymorphisms and iron overload in β-thalassemia major patients refractory to iron chelating therapy

• Главные авторы: Parinaz Zarghamian (Автор), Azita Azarkeivan (Автор), Ali Arabkhazaeli (Автор), Ahmad Mardani (Автор), Majid Shahabi (Автор)
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• Опубликовано: BMC, 2020-04-01T00:00:00Z.
• Предметы: article
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Abstract Background β Thalassemia is one of the most common groups of hereditary haemoglobinopathies. Affected people with thalassemia major are dependent on regular blood transfusion which on the long term leads to iron overload. Hepcidin is a peptide hormone and an important regulator of iron home...