Synthesis and cytotoxicity of the boron carrier pentagamaboronon-0-ol for boron neutron capture therapy against breast cancer

• Main Authors: Rohmad Yudi Utomo (Author), Febri Wulandari (Author), Dhania Novitasari (Author), Ratna Asmah Susidarti (Author), Mitsunori Kirihata (Author), Adam Hermawan (Author), Edy Meiyanto (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Boronic acid-containing curcumin analog, pentagamaboronon-0 (PGB-0), acts as a potential boron-carrier agent but has limited water solubility. Thus, a new compound (PGB-0-ol) with better chemical and pharmacological properties than PGB-0 has been synthesized. Molecular docking was performed using a...