Hyaluronic acid reduction-sensitive polymeric micelles achieving co-delivery of tumor-targeting paclitaxel/apatinib effectively reverse cancer multidrug resistance

• Main Authors: Xiaoqing Zhang (Author), Xiaomei Ren (Author), Jiayin Tang (Author), Jiangtao Wang (Author), Xiang Zhang (Author), Peng He (Author), Chang Yao (Author), Weihe Bian (Author), Lizhu Sun (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multidrug resistance (MDR) of cancer cells is a significant challenge in chemotherapy, highlighting the urgent medical need for simple and reproducible strategies to reverse this process. Here, we report the development of an active tumor-targeting and redox-responsive nanoplatform (PA-ss-NP) using...