Hyaluronic acid reduction-sensitive polymeric micelles achieving co-delivery of tumor-targeting paclitaxel/apatinib effectively reverse cancer multidrug resistance

• Hlavní autoři: Xiaoqing Zhang (Autor), Xiaomei Ren (Autor), Jiayin Tang (Autor), Jiangtao Wang (Autor), Xiang Zhang (Autor), Peng He (Autor), Chang Yao (Autor), Weihe Bian (Autor), Lizhu Sun (Autor)
• Médium: Kniha
• Vydáno: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Multidrug resistance (MDR) of cancer cells is a significant challenge in chemotherapy, highlighting the urgent medical need for simple and reproducible strategies to reverse this process. Here, we report the development of an active tumor-targeting and redox-responsive nanoplatform (PA-ss-NP) using...