Hyaluronic acid reduction-sensitive polymeric micelles achieving co-delivery of tumor-targeting paclitaxel/apatinib effectively reverse cancer multidrug resistance

• Auteurs principaux: Xiaoqing Zhang (Auteur), Xiaomei Ren (Auteur), Jiayin Tang (Auteur), Jiangtao Wang (Auteur), Xiang Zhang (Auteur), Peng He (Auteur), Chang Yao (Auteur), Weihe Bian (Auteur), Lizhu Sun (Auteur)
• Format: Livre
• Publié: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Multidrug resistance (MDR) of cancer cells is a significant challenge in chemotherapy, highlighting the urgent medical need for simple and reproducible strategies to reverse this process. Here, we report the development of an active tumor-targeting and redox-responsive nanoplatform (PA-ss-NP) using...