Hyaluronic acid reduction-sensitive polymeric micelles achieving co-delivery of tumor-targeting paclitaxel/apatinib effectively reverse cancer multidrug resistance

• Autori principali: Xiaoqing Zhang (Autore), Xiaomei Ren (Autore), Jiayin Tang (Autore), Jiangtao Wang (Autore), Xiang Zhang (Autore), Peng He (Autore), Chang Yao (Autore), Weihe Bian (Autore), Lizhu Sun (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Multidrug resistance (MDR) of cancer cells is a significant challenge in chemotherapy, highlighting the urgent medical need for simple and reproducible strategies to reverse this process. Here, we report the development of an active tumor-targeting and redox-responsive nanoplatform (PA-ss-NP) using...