Adrenergic Blockade by Nebivolol to Suppress Oral Squamous Cell Carcinoma Growth via Endoplasmic Reticulum Stress and Mitochondria Dysfunction

• Main Authors: Qian Chen (Author), Han Jiang (Author), Zhen Wang (Author), Lu-Yao Cai (Author), Yu-Chen Jiang (Author), Liang Xie (Author), Yu Zhou (Author), Xin Zeng (Author), Ning Ji (Author), Ying-Qiang Shen (Author), Qian-Ming Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adrenergic nerve fibers in the tumor microenvironment promote tumor growth and represent a potential target for cancer therapy. However, the effectiveness of targeting adrenergic nerve fibers for oral squamous cell carcinoma (OSCC) therapy needs to be evaluated by preclinical data. Herein, the 4NQO-...