Inflammation Pharmacological Reaction and YMDD Mutational Patterns in Lamivudine Therapeutics Hepatitis B Virus

• Main Authors: Hongcan Liu (Author), Zemin Wan (Author), Lanhui She (Author), Yajuan Zhu (Author), Zhiliang Cai (Author), Bin Wu (Author), Qizhen Zhuang (Author), Peifeng Ke (Author), Xinzhong Wu (Author), Zhuo Li (Author), Xianzhang Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Emergence of tyrosine-methionine-aspartate-aspartate (YMDD) motif in reverse transcriptase is a serious problem in chronic hepatitis B(CHB) patients after Lamivudine (LAM) therapy. However, the relationship between inflammation pharmacological reaction and YMDD mutational patterns o...