Systemic and Local Administration of Antimicrobial and Cell Therapies to Prevent Methicillin-Resistant Staphylococcus epidermidis-Induced Femoral Nonunions in a Rat Model

• Main Authors: Arianna B. Lovati (Author), Lorenzo Drago (Author), Marta Bottagisio (Author), Matilde Bongio (Author), Marzia Ferrario (Author), Silvia Perego (Author), Veronica Sansoni (Author), Elena De Vecchi (Author), Carlo L. Romanò (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

S. epidermidis is responsible for biofilm-related nonunions. This study compares the response to S. epidermidis-infected fractures in rats systemically or locally injected with vancomycin or bone marrow mesenchymal stem cells (BMSCs) in preventing the nonunion establishment. The 50% of rats receivin...