Metabolomics and Network Analyses Reveal Phenylalanine and Tyrosine as Signatures of Anthracycline-Induced Hepatotoxicity
The chemotherapy drug doxorubicin (DOX) is an anthracycline with over 30% incidence of liver injury in breast cancer patients, yet the mechanism of its hepatotoxicity remains unclear. To identify potential biomarkers for anthracycline-induced hepatotoxicity (AIH), we generated clinically-relevant mo...
Saved in:
Main Authors: | Peipei Liu (Author), Jing Wu (Author), Xinyue Yu (Author), Linling Guo (Author), Ling Zhao (Author), Tao Ban (Author), Yin Huang (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2023-05-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Metabolomics Reveals the Efficacy of Caspase Inhibition for Saikosaponin D-Induced Hepatotoxicity
by: Qian-qian Zhang, et al.
Published: (2018) -
Study on Hepatotoxicity of Rhubarb Based on Metabolomics and Network Pharmacology
by: Li S, et al.
Published: (2021) -
Aromatic Amino Acids: Phenylalanine and Tyrosine in Patients with Hypertension and Coronary Artery Disease
by: A. V. Krivova, et al.
Published: (2022) -
Metabolomics Reveals Molecular Signatures for Psoriasis Biomarkers and Drug Targets Discovery
by: Song Q, et al.
Published: (2023) -
Bruton's Tyrosine Kinase Inhibitor Zanubrutinib Effectively Modulates Cancer Resistance by Inhibiting Anthracycline Metabolism and Efflux
by: Lucie Čermáková, et al.
Published: (2022)