Deciphering the possible role of MmpL7 efflux pump in SQ109 resistance in Mycobacterium tuberculosis

• Main Authors: Wei Jing (Author), Fuzhen Zhang (Author), Yuanyuan Shang (Author), Wenhui Shi (Author), Cong Yao (Author), Xuxia Zhang (Author), Naihui Chu (Author), Jie Lu (Author), Jinfeng Yuan (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background SQ109 is a promising candidate drug for the treatment of patients with drug-resistant tuberculosis (DR-TB). The purpose of this study was to investigate the activity of SQ109 against clinical isolates of Mycobacterium tuberculosis (MTB) from patients with multidrug-resistant TB (...