Tempol Supplementation Restores Diaphragm Force and Metabolic Enzyme Activities in mdx Mice

• Main Authors: David P. Burns (Author), Izza Ali (Author), Clement Rieux (Author), James Healy (Author), Greg Jasionek (Author), Ken D. O'Halloran (Author)
• Format: Book
• Published: MDPI AG, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Duchenne muscular dystrophy (DMD) is characterized by striated muscle weakness, cardiomyopathy, and respiratory failure. Since oxidative stress is recognized as a secondary pathology in DMD, the efficacy of antioxidant intervention, using the superoxide scavenger tempol, was examined on functional a...