Design, synthesis and biological evaluation of a series of dianilinopyrimidines as EGFR inhibitors
This paper described our efforts to develop dianilinopyrimidines as novel EGFR inhibitors. All the target compounds were tested for inhibitory effects against wild type EGFR (EGFRwt) and three tumour cells, including A549, PC-3, and HepG2. Some of the compounds performed well in antitumor activities...
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Taylor & Francis Group,
2022-12-01T00:00:00Z.
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