Effects of 3,4-Methylenedioxymethamphetamine on Conditioned Fear Extinction and Retention in a Crossover Study in Healthy Subjects

• Main Authors: Patrick Vizeli (Author), Isabelle Straumann (Author), Urs Duthaler (Author), Nimmy Varghese (Author), Anne Eckert (Author), Martin P. Paulus (Author), Victoria Risbrough (Author), Matthias E. Liechti (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: 3,4-Methylenedioxymethamphetamine (MDMA) has shown initial promise as an adjunct in psychotherapy to treat posttraumatic stress disorder (PTSD). Its efficacy and safety have been demonstrated across phase I-III studies. However, the mechanism underlying the potential utility of MDMA to t...