Cotinine and 6-Hydroxy-L-Nicotine Reverses Memory Deficits and Reduces Oxidative Stress in Aβ_25-35-Induced Rat Model of Alzheimer's Disease

• Principais autores: Razvan Stefan Boiangiu (Autor), Marius Mihasan (Autor), Dragos Lucian Gorgan (Autor), Bogdan Alexandru Stache (Autor), Brindusa Alina Petre (Autor), Lucian Hritcu (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2020-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The nicotinic derivatives, cotinine (COT), and 6-hydroxy-L-nicotine (6HLN), showed promising cognitive-improving effects without exhibiting the nicotine's side-effects. Here, we investigated the impact of COT and 6HLN on memory impairment and the oxidative stress in the Aβ<sub>25-35</s...