Indel sensitive and comprehensive variant/mutation detection from RNA sequencing data for precision medicine

• Glavni autori: Naresh Prodduturi (Autor), Aditya Bhagwate (Autor), Jean-Pierre A. Kocher (Autor), Zhifu Sun (Autor)
• Format: Knjiga
• Izdano: BMC, 2018-09-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Background RNA-seq is the most commonly used sequencing application. Not only does it measure gene expression but it is also an excellent media to detect important structural variants such as single nucleotide variants (SNVs), insertion/deletion (Indels) or fusion transcripts. However, dete...