Effect of Dispersion Medium on Pharmacokinetic Profile of Rotigotine Crystalline Suspension following Subcutaneous Injection

• Egile Nagusiak: Min Seop Kim (Egilea), Myoung Jin Ho (Egilea), Min Yeong Joung (Egilea), Yong Seok Choi (Egilea), Myung Joo Kang (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Rotigotine (RTG) is prescribed as a once-daily transdermal patch for managing early Parkinson's disease (PD), which presents issues such as skin irritation and poor patient adherence. Therefore, the aims of the present study were to formulate aqueous and oily vehicle-based RTG crystalline suspe...