Pentagalloylglucose alleviates acetaminophen-induced acute liver injury by modulating inflammation via cGAS-STING pathway

• Main Authors: Congyang Zheng (Author), Yuanyuan Chen (Author), Tingting He (Author), Ye Xiu (Author), Xu Dong (Author), Xianling Wang (Author), Xinru Wen (Author), Chengwei Li (Author), Qing Yao (Author), Simin Chen (Author), Xiaoyan Zhan (Author), Lili Gao (Author), Zhaofang Bai (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The cGAS-STING pathway is an important component of the innate immune system and plays significant role in acetaminophen-induced liver injury (AILI). Pentagalloylglucose (PGG) is a natural polyphenolic compound with various beneficial effects, including anti-cancer, antioxidant,...