HSP60 chaperone deficiency disrupts the mitochondrial matrix proteome and dysregulates cholesterol synthesis

Objective: Mitochondrial proteostasis is critical for cellular function. The molecular chaperone HSP60 is essential for cell function and dysregulation of HSP60 expression has been implicated in cancer and diabetes. The few reported patients carrying HSP60 gene variants show neurodevelopmental delay...

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Main Authors: Cagla Cömert (Author), Kasper Kjær-Sørensen (Author), Jakob Hansen (Author), Jasper Carlsen (Author), Jesper Just (Author), Brandon F. Meaney (Author), Elsebet Østergaard (Author), Yonglun Luo (Author), Claus Oxvig (Author), Lisbeth Schmidt-Laursen (Author), Johan Palmfeldt (Author), Paula Fernandez-Guerra (Author), Peter Bross (Author)
Format: Book
Published: Elsevier, 2024-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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