Activation of AMP-Activated Protein Kinase-Sirtuin 1 Pathway Contributes to Salvianolic Acid A-Induced Browning of White Adipose Tissue in High-Fat Diet Fed Male Mice

• Main Authors: Jianfei Lai (Author), Qianyu Qian (Author), Qinchao Ding (Author), Li Zhou (Author), Ai Fu (Author), Zhongyan Du (Author), Cui Wang (Author), Zhenyuan Song (Author), Songtao Li (Author), Xiaobing Dou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Salvianolic acid A (Sal A), a natural polyphenolic compound extracted from Radix Salvia miltiorrhiza (Danshen), exhibits exceptional pharmacological activities against cardiovascular diseases. While a few studies have reported anti-obesity properties of Sal A, the underlying mechanisms a...