Assessment of Aptamer as a Potential Drug Targeted Delivery for Retinal Angiogenesis Inhibition

Assessment of Aptamer as a Potential Drug Targeted Delivery for Retinal Angiogenesis Inhibition

AT11-L0 is an aptamer derivative of AS1411 composed of G-rich sequences that can adopt a G-quadruplex (G4) structure and target nucleolin (NCL), a protein that acts as a co-receptor for several growth factors. Hence, this study aimed to characterize the AT11-L0 G4 structure and its interaction with...

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Main Authors: David Moreira (Author), Jéssica Lopes-Nunes (Author), Fátima Milhano Santos (Author), Maria Paula Cabral Campello (Author), Maria Cristina Oliveira (Author), António Paulo (Author), Cândida Tomaz (Author), Carla Cruz (Author)
Format: Book
Published: MDPI AG, 2023-05-01T00:00:00Z.
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3rd Floor Main Library

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