P2X7 Receptor-Mediated Inflammation in Cardiovascular Disease

• Główni autorzy: Junteng Zhou (Autor), Zhichao Zhou (Autor), Xiaojing Liu (Autor), Hai-Yan Yin (Autor), Yong Tang (Autor), Xin Cao (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Purinergic P2X7 receptor, a nonselective cation channel, is highly expressed in immune cells as well as cardiac smooth muscle cells and endothelial cells. Its activation exhibits to mediate nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome activation, resulting in the rele...