From PROTAC to TPD: Advances and Opportunities in Targeted Protein Degradation

• Главные авторы: Siqi Wang (Автор), Fuchu He (Автор), Chunyan Tian (Автор), Aihua Sun (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2024-01-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

PROTAC is a rapidly developing engineering technology for targeted protein degradation using the ubiquitin-proteasome system, which has promising applications for inflammatory diseases, neurodegenerative diseases, and malignant tumors. This paper gives a brief overview of the development and design...