Mismatch Repair Status Characterization in Oncologic Pathology: Taking Stock of the Real-World Possibilities
The mismatch repair (MMR) system has a key role in supporting the DNA polymerase proofreading function and in maintaining genome stability. Alterations in the MMR genes are driving events of tumorigenesis, tumor progression, and resistance to therapy. These genetic scars may occur in either heredita...
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MDPI AG,
2021-04-01T00:00:00Z.
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