The NMR studies of CMP inhibition of polysialylation

• Asıl Yazarlar: Bo Lu (Yazar), Si-Ming Liao (Yazar), Xue-Hui Liu (Yazar), Shi-Jie Liang (Yazar), Jun Huang (Yazar), Mei Lin (Yazar), Li Meng (Yazar), Qing-Yan Wang (Yazar), Ri-Bo Huang (Yazar), Guo-Ping Zhou (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The overexpression of polysialic acid (polySia) on neural cell adhesion molecules (NCAM) promotes hypersialylation, and thus benefits cancer cell migration and invasion. It has been proposed that the binding between the polysialyltransferase domain (PSTD) and CMP-Sia needs to be inhibited in order t...