Methylphenidate Multiphasic Release Tablet: Bioequivalence Assessment between Two Formulations Administered under Fasting and Fed Conditions

• Main Authors: Marcelo Gomes Davanço (Author), Jessica Meulman (Author), Thalita Martins da Silva (Author), Fernando Costa (Author), Karini Bruno Bellorio (Author), Iram Moreira Mundim (Author), Ana Carolina Costa Sampaio (Author), Leonardo de Souza Teixeira (Author), Celso Francisco Pimentel Vespasiano (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Methylphenidate hydrochloride is used to treat children, adolescents, and adults with attention deficit/hyperactivity disorder (ADHD). Multiphasic release formulation has been used to control drug levels, mainly during children's school period. This study aimed to evaluate the bioequivalence be...