Current Evidence of Interleukin-6 Signaling Inhibitors in Patients With COVID-19: A Systematic Review and Meta-Analysis

• Main Authors: Qi Han (Author), Mingyue Guo (Author), Yue Zheng (Author), Ying Zhang (Author), Yanshan De (Author), Changchang Xu (Author), Lin Zhang (Author), Ruru Sun (Author), Ying Lv (Author), Yan Liang (Author), Feng Xu (Author), Jiaojiao Pang (Author), Yuguo Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Interleukin-6 (IL-6) is known to be detrimental in coronavirus disease 2019 (COVID-19) because of its involvement in driving cytokine storm. This systematic review and meta-analysis aimed to assess the safety and efficacy of anti-IL-6 signaling (anti-IL6/IL-6R/JAK) agents on COVID-19 bas...