Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1: a Phase IIa randomised controlled study

• Main Authors: Sofie Rutsaert (Author), Jean-Marc Steens (Author), Paul Gineste (Author), Basiel Cole (Author), Sam Kint (Author), P. Noel Barrett (Author), Jamal Tazi (Author), Didier Scherrer (Author), Hartmut J. Ehrlich (Author), Linos Vandekerckhove (Author)
• Format: Book
• Published: Elsevier, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: To assess the safety and tolerability as well as antiretroviral impact of ABX464, an oral investigational drug with a novel mechanism of HIV-1 inhibition (ClinicalTrials.gov NCT02735863). Methods: Randomised, double-blind, placebo-controlled, Phase IIa study in individuals living with HI...