Engineering of Stimulus-Responsive Pirfenidone Liposomes for Pulmonary Delivery During Treatment of Idiopathic Pulmonary Fibrosis

• Main Authors: Meishan Han (Author), Yingjian Song (Author), Sha Liu (Author), Xiaoyan Lu (Author), Linyu Su (Author), Meixuan Liu (Author), Xiaosu Zhu (Author), Kaoxiang Sun (Author), Yanan Lu (Author), Aiping Wang (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Fag: article
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Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by progressive and irreversible loss of lung function. Clinically safe and efficacious drug treatments for IPF are lacking. Pirfenidone (an anti-inflammatory, antioxidant and anti-fibrotic small-molecule drug) is consi...